Shingles In Pregnancy: Causes, Symptoms And Treatment

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Shingles is a viral infection that manifests as painful rashes or blisters, often on one side of the body or face(1)(2). Shingles or herpes zoster and chickenpox share a common causative agent, varicella zoster virus.If you are affected with shingles in pregnancy, it is not known to cause fetal complications.Although rare, the availability of different pregnancy-safe treatments can help alleviate the symptoms of shingles and discomfort. In general, around one in every three people in the US develop shingles and are mostly above 50 years(3).

The below post discusses shingles in pregnancy, including its causes, symptoms, and treatments.

带状疱疹的病因是什么?

Shingles is a secondary infection of chickenpox contracted from another person containing the virus.It remains dormant in theposterior root ganglionⁱXA group of nerve cells in the dorsal root of a spinal nerve房颤ter the primary infection (chickenpox) and travels to the skin upon reactivation, resulting in shingles(4).

Besides the advancing age and the body’s natural changes, a person who has had chickenpox may develop shingles later in life from other factors as follows(4)(5):

• Underlying health conditions, such as HIV or cancer that compromise the immune system

• Exposure to radiation or chemotherapy

• Lack of nutrition

• Stress and fatigue

• Intake ofimmunosuppressantsⁱXDrugs that reduce the body’s immune responses, including cyclosporin or corticosteroids

• Exertion of pressure on the nerve root

What Are The Symptoms Of Shingles In Pregnancy?

The manifestation of shingles usually proceeds in stages. These are(2)(6):

Early symptoms:

• 疼痛或刺痛的感觉在受影响的地区

• MalaiseⁱXA state of weakness, general discomfort, disease, or just not feeling wellor headache

• High temperature

• Sensitivity in the area of the skin before the rash occurs

Later symptoms:

• Development of painful rash in the tingling area of the skin about one to five days after theearly symptoms

• 形成的充满液体的水泡痒rash after seven to ten days

Symptoms can appear anywhere in the body— around the stomach, the chest, and the eyes. However, they typically occur only on one side of the body and are expected to subside within two tofour weekswithout posing any threat to the baby orthe pregnancy.

When To See A Doctor?

If you have contacted an infected patient, you should consult a healthcare provider immediately for timely treatment.This might help shorten the disease’s duration and reduce the severity. A prolonged manifestation may cause pregnancy complications if not addressed in time.

How Is Shingles In Pregnancy Diagnosed?

Upon manifestation, the healthcare provider may want to know if you’ve had chickenpox in the past and any direct contact with an infected person. Diagnosis involves a lab test, where a small portion of the rash is scraped and examined. Upon confirmation, the healthcare provider will proceed with effective and pregnancy-safe treatment(2).

How Is Shingles In Pregnancy Treated?

Below are some medications and home measures you can follow only after consultation with a healthcare provider(7)(8):

1. Antiviral drugs:The category B antiviral medication for shingles recommended in the earlystages of pregnancyinclude acyclovir, valacyclovir, and famciclovir. The medicines are likely to be effective when taken within 72 hours of blister eruption.

2. Painkillers:Analgesics include category B drugs, such as acetaminophen and short-termopioid medicinesⁱXA kind of medication obtained from the opium poppy plant and is used to manage moderate to severe pain.Most opioid medicines except for codeine are safe for pregnancy with proper monitoring.Acetaminophen is usually prescribed for relief from severeneuritisⁱXA condition that causes inflammation of one or more nerves of the peripheral nervous system, primarily because of infection or injurypain.

2. Self-care measures:Some recommended home measures include:

• Cold compresses on the rashes or blisters for pain relief

• Lukewarm baths

• 炉甘石液和的应用other creams (pramoxine or menthol) for relief from itchiness

Note:Some medications are not suitable for pregnant people, and the over-the-counter medicines should not be taken without a doctor’s prescription.

Can You Prevent Shingles?

Prevention of shingles can be achieved only by taking the Herpes zoster vaccine or the shingles vaccine, Shingrix. CDC recommends it for people of 50 years and above. The vaccine is given in two doses, with the second dose administered after two tosix monthsof the first one. Shingrix is more than 90% effective, and you will be immune at least for about seven years from the time of vaccination(9).

Ifpregnant womencontract the disease, they should not get the vaccination until post-delivery. Women who have had Shingrix vaccination are recommended to wait for at least one month toget pregnant(10). Since the virus can be transferred from a person with shingles to another person, it is better to stay away from infected people for the safety of yourself and your fetus.

What Are The Complications Of Shingles During Pregnancy?

Complications may arise if the symptoms of shingles persist for longer than four weeks. They can include(2)(7):

• Postherpetic neuralgia (PHN):Patients with severe pain or compromised senses during the infection can be at a higher risk of PHN. It is characterized by acute pain that can last for 30 to 90 days even after the blisters subside. Early treatment can help prevent further problems with category B opioids as it is the common and safe treatment choice.

• Secondary bacterial infection:The rash may be further infected by a bacterial agent, which is not commonly seen in pregnant women. The healthcare provider may prescribe oral antibiotics for the bacterial infection, mostly for staphylococcal or streptococcal infections, for the baby’s safety.

• Vision impairment:If the rash develops around the eyes, it can compromise the vision of the infected person through an infection in the cornea. This can further lead to temporary or permanent loss of sight.

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