Ectopic Pregnancy: Causes, Symptoms, Treatment, And Risks

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What Is An Ectopic Pregnancy?

Ectopic pregnancy is a pregnancy that occurs outside the uterine endometrium. If left unmanaged, there is a risk for rupture and life-threatening bleeding. It is rare, affecting one in every 100 pregnancies(1).

The fertilized egg most commonly attaches to the fallopian tube in such a pregnancy, leading to a tubal pregnancy. It can also attach to the cervix, ovary, or somewhere in the abdominal cavity. In most cases, the fertilized egg cannot survive outside the womb in the gestational sac, and the growing tissue can damage surrounding tissues(2).

Read on to know more about the symptoms, causes, risk factors, diagnosis, and treatment for ectopic pregnancy.

Signs And Symptoms Of An Ectopic Pregnancy

Symptoms develop in the early stages of pregnancy and vary from woman to woman. Some women will develop no symptoms until pregnancy ruptures.

During early pregnancy, some women will begin to experience symptoms similar to that of a healthy pregnancy. They may include:

  • Missed menstrual period
  • Sore breasts
  • Upset stomach
  • Lowback painor pelvic pain
  • Vaginal spotting or bleeding
  • Abdominal painor tenderness
  • Mild cramping at one side of the pelvic region

protip_icon Quick fact
Low blood pressure is another symptom some women may experience due to blood loss from ectopic pregnancy rupture (15).

Around this phase, it is not easy to understand if it is a normal or ectopic pregnancy. But as the ectopic pregnancy develops, you could experience certain severe symptoms(3):
  • Sudden and severe pain in the abdomen, shoulder, neck or pelvis
  • Vaginal spottingor bleeding that is light to heavy
  • Dizziness, weakness or fainting
  • Rectal pressure

You should see your doctor if you know about the pregnancy and are experiencing these symptoms.

Causes Of An Ectopic Pregnancy

The exact reason for an ectopic pregnancy is unknown. However, the condition is likely to be associated with one or more of the following conditions(4):

  • Scarring or inflammation of the fallopian tubes from a previous infection, medical condition or surgery
  • Hormonal reasons
  • Birth defects
  • Genetic abnormalities
  • Medical conditions that influence the shape and condition of the reproductive system organs, such as fallopian tubes

Note that only your doctor can make the correct diagnosis and give you specific treatment options based on the probable cause and risk factors.

Risk Factors For Ectopic Pregnancy

Factors that increase the chances of an ectopic gestation include(4):

  • Maternal age of 35 years and more
  • Previous ectopic pregnancy
  • History offallopian tubeiXTube-like structures connecting the ovaries and uterus that help transport eggs for the fertilization process., abdominal or pelvic surgeries or multiple abortions
  • History ofpelvic inflammatory disease (PID)iXInfection in the female genital tract characterized by pelvic pain, fever, and abnormal vaginal discharge.
  • History ofendometriosisiXCondition in which tissue that lines a female uterus begins to develop outside the organ leading to pelvic pain and bleeding.
  • Sexually transmitted infections (STIs) such aschlamydiaiXInfectious, Sexually transmitted bacterial infection causing pain and abnormal discharge in women, sometimes linked to adverse pregnancy outcomes.orgonorrheaiXSexually transmitted bacterial infection, which, when untreated, may increase the risk of negative pregnancy outcomes.
  • Conception despiteintrauterine device (IUD)iXSmall, contraceptive copper device (in T shape), which, when placed inside the uterus, helps prevent pregnancy.ortubal ligation
  • Conception through fertility drugs and procedures
  • Cigarette smoking
  • Structural abnormalities in the fallopian tubes

protip_icon Research finds
Infertility, using estrogen- and progestin-containing oral contraceptives and in-vitro fertilization in the current pregnancy are additional risk factors for ectopic pregnancy (15).

If you think you are at risk, discuss with your obstetric or a fertility specialist to minimize the chances of ectopic pregnancies in the future.

How Is An Ectopic Pregnancy Diagnosed?

Diagnosing an ectopic pregnancy is tricky. If the symptoms suggest that you are experiencing an ectopic pregnancy, your doctor may(5):

If an ectopic pregnancy is confirmed based on the above findings, your doctor will suggest the best treatment plan.

Treating Ectopic Pregnancy

Ectopic pregnancies can be fatal to a pregnant woman. As the zygote cannot survive outside the uterus, it has to be immediately removed for the safety of the mother. Treatment may depend on the pregnancy stage, hormonal levels, and location of the ectopic pregnancy.

  • Medication: If your doctor determines that there are no chances of immediate complications, medicinal treatment is suggested. According to the American Family Physician (AFP), the common medication prescribed is methotrexate (Rheumatrex). This drug inhibits the growth of the quickly dividing cells or ectopic mass in this case.

It is available in the form of an injection and results in miscarriage-like symptoms including bleeding, cramping, and the passing of the trophoblast tissue. But the only downside with this treatment is that you will not conceive for several months after taking medicine(6).

  • Surgery: The embryo is removed using a procedure called laparoscopy.A small incision is made near the belly button, into which a tiny camera is passed for a better view.The surgeon then removes the pregnancy using surgical tools. Sometimes, the surgery can scar the fallopian tubes, which will then be either repaired (salpingostomy) or removed (salpingectomy)(7).
  • Emergency surgery:如果条件是导致异常沉重的流血ing or damage due to pregnancy loss, you may need immediate surgery using laparotomy. It involves an abdominal incision and removal of the ectopic mass. Also, the tube may be removed if it is ruptured(7).
protip_icon Point to consider
After receiving treatment for an ectopic pregnancy (medication or surgery), it may take some time for your body’s hCG level to decline. So, your menstrual cycles might not start to feel normal for a few cycles (16).

Are There Any Side Effects Of Surgery?

The possible side effects of surgery for ectopic pregnancy include bleeding, pain, fatigue, and infection(8). Your doctor will discuss these before the procedure.

Home Care After Surgery

Follow the doctor’s instructions to take care of the incision site at home. The primary goal is to keep it dry and clean as it heals. You should also check the incision for signs of infection regularly. This can be:

  • Severe and uncontrollable bleeding
  • A foul smell at the incision site
  • Tender to touch
  • Swelling and redness

You may also notice some light spotting and tiny blood clots after the surgery, which could last for nearly six weeks post-surgery.

Here are a few more self-care measures that may help you at home:

  • Avoid lifting anything heavy
  • Have lots of fluids totreat constipation
  • Rest as much as you can
  • Avoid sexual intercourse,douchingiXA method of cleansing (flushing) the inner vaginal region with water and other liquids., and using tampons to give some rest to the pelvic area

See your doctor if you feel any pain or that something is not right.

Can You Prevent Ectopic Pregnancy?

No, ectopic pregnancy cannot be prevented entirely, but there are certain ways to reduce the chances of developing it(9).

  • Use condoms during intercourse to avoid the risk of sexually transmitted infections and pelvic inflammatory diseases.
  • Avoid sex with multiple partners.
  • Quit smoking before you try for pregnancy.

Next, we address some common queries for your better understanding of the condition

Frequently Asked Questions

1. Can a baby survive in an ectopic pregnancy?

No, the baby cannot survive in an ectopic pregnancy as it is formed outside the womb. The tissues outside the uterus cannot provide enough blood supply that the fetus needs to survive.

2. How soon would you know if you have an ectopic pregnancy?

You can detect an ectopic pregnancy as early as four to five weeks. Symptoms to look for include a missed period, positive pregnancy test result, severe abdominal pain, spotting, dizziness, or rectal pressure. However, not everyone can detect an ectopic pregnancy through these early signs and may need to get an ultrasound scan.

3. Can a pregnancy test detect an ectopic pregnancy?

Positive urine or blood pregnancy test can be seen in ectopic pregnancy as well. Beta-hCG levels less than 1,500 mIU per mL may indicate an ectopic pregnancy. However, lower hCG levels can also be seen in a failing pregnancy. The lack of doubling of hCG hormones in 48 hours can indicate ectopic pregnancy in most cases. Diagnostic ultrasonography is required to confirm ectopic pregnancy(10).

4. How long after ectopic pregnancy, will I get my period?

You will get your first period within six weeks after the ectopic pregnancy is terminated. It might not be like a normal period, but heavier or lighter and more painful(11).

5. Can you have an ectopic pregnancy without bleeding?

In some cases, an ectopic pregnancy is absorbed, and there will be no symptoms of vaginal bleeding. According to Andy Raffles, author of ‘Mother and Baby Health: The A-Z of Pregnancy, Birth and Beyond,’ modern ultrasound scans detect ectopic pregnancies that occur without symptoms such as pain or spotting.

6. How painful is an ectopic pregnancy?

Ectopic pregnancy may cause dull and mild to sharp and severe pain(12). You may experience pain in the abdomen, pelvis, and also the neck and shoulder regions.

7. How long does it take to heal from an ectopic pregnancy?

The time for healing from an ectopic pregnancy treatment, whether with medication or surgery, would be four to six weeks(13).

8. Can you remove an ectopic pregnancy without surgery?

Yes, if the fallopian tube has not ruptured and the pregnancy is in its initial stages, your doctor would give you an injection to remove the ectopic pregnancy.

9. Can you have an ectopic pregnancy without a positive test?

Yes, there are chances you could have an ectopic pregnancy without a positive result for a home pregnancy test because of the low levels of the hCG hormone.

10. Can you get pregnant after you have had an ectopic pregnancy?

Most women who experience an ectopic pregnancy can have normal pregnancies in the future. It does not matter if one of the fallopian tubes was removed since one healthy working tube is enough to help the fertilization. The earlier the ectopic pregnancy is removed, the lesser the damage to the tube, the higher are the chances of conception again(14).

If an infection or sexually transmitted disease were the cause for your ectopic pregnancy, then getting the condition treated improves the chances of conception. But, if the ectopic pregnancy occurs due to tubal ligation or exposure to diethylstilbestrol (DES), the chances of a healthy pregnancy are lesser.

If you’ve had an ectopic pregnancy, check with your doctor before you plan for the next pregnancy. Ensure that you give enough time for yourself to heal emotionally and physically, especially if you’ve had surgery to treat it. Dealing with an ectopic pregnancy, when you want to have a child, is not easy. If necessary, join a counseling group or talk to a therapist.

Do you have any experiences to share? Let us know in the comment section below.

Key Pointers

  • Ectopic pregnancy refers to the implantation of the embryo outside the uterus, commonly in the fallopian tube.
  • Symptoms of ectopic pregnancy may include pregnancy symptoms, such as nausea and breast tenderness, as well as abdominal pain, vaginal bleeding, hypotension, and fainting.
  • Underlying health conditions, inflammation of the fallopian tubes, and hormonal issues are common causes of ectopic pregnancy.
  • The risk of ectopic pregnancy may increase in individuals with a history of similar conditions, surgeries, STIs, and advanced maternal age.
  • Treatment for ectopic pregnancy typically involves medications or surgery, depending on the severity of the condition.


References:

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3.Ectopic Pregnancy;UCSB SexInfo (2018)
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5. Heather Murray et al.;Diagnosis and treatment of ectopic pregnancy;CMAJ (2005)
6. Hansa Dhar et al.;Methotrexate Treatment of Ectopic Pregnancy: Experience at Nizwa Hospital with Literature Review;Oman Med J (2011)
7. BS Duggal et al.;Laparoscopic Management of Ectopic Pregnancies;Med J Armed Forces India (2004)
8.Ectopic Pregnancy;美国妇产科医师的Gynecologists
9. Albers K;Comprehensive care in the prevention of ectopic pregnancy and associated negative outcomes;Midwifery Today Int Midwife (2007)
10.Ectopic pregnancy;American Family Physician
11.Your body after an ectopic pregnancy;The ectopic pregnancy test
12. Constance J. Creech;Ectopic Pregnancy;JOURNAL OF THE AMERICAN ACADEMY OF NURSE PRACTITIONERS
13.Treatment – Ectopic pregnancy;The National Health Service in England, NHS Scotland, NHS Wales, and Health and Social Care in Northern Ireland
14. Chanda Karki et al.;Ectopic Pregnancy and its Effect on Future Fertility;South Asian Federation of Obstetrics and Gynecology (2009)
15. Antonette T. Dulay;Ectopic Pregnancy;MSD Manual
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